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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
22.12
Human Site:
S273
Identified Species:
37.44
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S273
E
F
E
D
T
P
T
S
Q
L
T
I
D
E
F
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S415
E
F
E
D
T
P
T
S
Q
L
T
I
D
E
F
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
L211
S
M
T
A
L
R
L
L
Q
R
M
K
R
D
W
Dog
Lupus familis
XP_548005
637
70371
C249
R
I
D
L
E
G
E
C
D
P
P
S
Y
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
S273
E
F
E
D
T
P
T
S
Q
L
T
I
D
E
F
Rat
Rattus norvegicus
NP_001100231
686
74096
S283
E
F
E
D
T
P
T
S
Q
L
T
I
D
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
S274
E
F
E
Y
T
P
T
S
Q
L
T
I
D
E
F
Frog
Xenopus laevis
NP_001088063
660
73751
F267
L
R
K
R
L
T
E
F
E
D
T
P
T
S
Q
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
S272
E
F
E
E
T
P
T
S
S
L
T
I
D
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
G274
E
F
A
E
T
P
S
G
G
L
T
L
E
E
F
Honey Bee
Apis mellifera
XP_623775
648
73504
R260
K
V
H
E
S
T
L
R
K
R
L
I
E
F
G
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
G268
E
F
S
Q
T
P
S
G
S
L
T
I
D
E
F
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
G275
E
F
E
E
T
P
S
G
K
L
T
I
D
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
R208
D
A
V
K
L
A
Q
R
M
S
K
D
W
M
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
6.6
0
N.A.
100
100
N.A.
N.A.
93.3
6.6
86.6
N.A.
53.3
6.6
66.6
73.3
P-Site Similarity:
100
100
20
6.6
N.A.
100
100
N.A.
N.A.
93.3
20
93.3
N.A.
80
40
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
29
0
0
0
0
8
8
0
8
58
8
0
% D
% Glu:
65
0
50
29
8
0
15
0
8
0
0
0
15
65
0
% E
% Phe:
0
65
0
0
0
0
0
8
0
0
0
0
0
8
72
% F
% Gly:
0
0
0
0
0
8
0
22
8
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
65
0
0
0
% I
% Lys:
8
0
8
8
0
0
0
0
15
0
8
8
0
0
0
% K
% Leu:
8
0
0
8
22
0
15
8
0
65
8
8
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
65
0
0
0
8
8
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
43
0
0
0
0
0
8
% Q
% Arg:
8
8
0
8
0
8
0
15
0
15
0
0
8
0
0
% R
% Ser:
8
0
8
0
8
0
22
43
15
8
0
8
0
8
0
% S
% Thr:
0
0
8
0
65
15
43
0
0
0
72
0
8
8
0
% T
% Val:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _